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Red Blood Cell Aggregation

Red Blood Cell Aggregation

Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology similar to a stack of coins. Known as rouleaux these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic clinical and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants mechanisms and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field this is an invaluable resource for basic science medical and clinical researchers; graduate stu

GBP 59.99
1

Reinsurance and the Law of Aggregation Event Occurrence Cause

Reinsurance and the Law of Aggregation Event Occurrence Cause

In excess of loss reinsurance the reinsurer covers the amount of a loss exceeding the policy’s deductible but not piercing its cover limit. Accordingly a policy’s quantitative scope of cover is significantly affected by the parties’ agreement of a deductible and a cover limit. Yet the examination of whether a loss has exceeded deductible or cover limit necessitates an educated understanding of what constitutes one loss. In so-called aggregation clauses the parties to (re-)insurance contracts regularly provide that multiple individual losses are to be added together for presenting one loss to the reinsurer when they arise from the same event occurrence catastrophe cause or accident. Aggregation mechanisms are one of the core instruments for structuring reinsurance contracts. This book systematically examines each element of an aggregation mechanism tracing the inconsistent usage of aggregation language in the markets and scrutinizing the tests developed by courts and arbitral tribunals. In doing so it seeks to support insurers reinsurers brokers and lawyers in drafting aggregation clauses and in settling claims. Focusing on an analysis of primary sources particularly judicial decisions the book interprets each judicial decision to describe a system of inter-related rules collating organising and describing the English law of aggregation as applied by the courts and arbitral tribunals. It further draws a comparison between the English position and the corresponding rules in the Principles of Reinsurance Contract Law (PRICL). | Reinsurance and the Law of Aggregation Event Occurrence Cause

GBP 36.99
1

A Theory of Group Structures Volume I: Basic Theory

Arbuscular Mycorrhizal Fungi For Nutrient Abiotic and Biotic Stress Management in Rice

Quantitative Trading Algorithms Analytics Data Models Optimization

A Theory of Group Structures Volume II: Empirical Tests

Building Wireless Sensor Networks Theoretical and Practical Perspectives

Prion Biology Research and Advances

Revival: Environmental Particles (1993) Volume 2

Netgear 8 Port PoE Gbit Smart Managed Pro Switch

Introduction to High-Dimensional Statistics

Introduction to High-Dimensional Statistics

Praise for the first edition: [This book] succeeds singularly at providing a structured introduction to this active field of research. … it is arguably the most accessible overview yet published of the mathematical ideas and principles that one needs to master to enter the field of high-dimensional statistics. … recommended to anyone interested in the main results of current research in high-dimensional statistics as well as anyone interested in acquiring the core mathematical skills to enter this area of research. —Journal of the American Statistical Association Introduction to High-Dimensional Statistics Second Edition preserves the philosophy of the first edition: to be a concise guide for students and researchers discovering the area and interested in the mathematics involved. The main concepts and ideas are presented in simple settings avoiding thereby unessential technicalities. High-dimensional statistics is a fast-evolving field and much progress has been made on a large variety of topics providing new insights and methods. Offering a succinct presentation of the mathematical foundations of high-dimensional statistics this new edition: Offers revised chapters from the previous edition with the inclusion of many additional materials on some important topics including compress sensing estimation with convex constraints the slope estimator simultaneously low-rank and row-sparse linear regression or aggregation of a continuous set of estimators. Introduces three new chapters on iterative algorithms clustering and minimax lower bounds. Provides enhanced appendices minimax lower-bounds mainly with the addition of the Davis-Kahan perturbation bound and of two simple versions of the Hanson-Wright concentration inequality. Covers cutting-edge statistical methods including model selection sparsity and the Lasso iterative hard thresholding aggregation support vector machines and learning theory. Provides detailed exercises at the end of every chapter with collaborative solutions on a wiki site. Illustrates concepts with simple but clear practical examples.

GBP 74.99
1

State-Space Methods for Time Series Analysis Theory Applications and Software

State-Space Methods for Time Series Analysis Theory Applications and Software

The state-space approach provides a formal framework where any result or procedure developed for a basic model can be seamlessly applied to a standard formulation written in state-space form. Moreover it can accommodate with a reasonable effort nonstandard situations such as observation errors aggregation constraints or missing in-sample values. Exploring the advantages of this approach State-Space Methods for Time Series Analysis: Theory Applications and Software presents many computational procedures that can be applied to a previously specified linear model in state-space form. After discussing the formulation of the state-space model the book illustrates the flexibility of the state-space representation and covers the main state estimation algorithms: filtering and smoothing. It then shows how to compute the Gaussian likelihood for unknown coefficients in the state-space matrices of a given model before introducing subspace methods and their application. It also discusses signal extraction describes two algorithms to obtain the VARMAX matrices corresponding to any linear state-space model and addresses several issues relating to the aggregation and disaggregation of time series. The book concludes with a cross-sectional extension to the classical state-space formulation in order to accommodate longitudinal or panel data. Missing data is a common occurrence here and the book explains imputation procedures necessary to treat missingness in both exogenous and endogenous variables. Web ResourceThe authors’ E4 MATLAB® toolbox offers all the computational procedures administrative and analytical functions and related materials for time series analysis. This flexible powerful and free software tool enables readers to replicate the practical examples in the text and apply the procedures to their own work. | State-Space Methods for Time Series Analysis Theory Applications and Software

GBP 48.99
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Transformation in Healthcare with Emerging Technologies

Netgear GS752TP 52 Port Gigabit Ethernet Smart Switch with 4 SFP Ports

Reading Images for Knowledge Building Analyzing Infographics in School Science

The Routledge Handbook of Elections Voting Behavior and Public Opinion

Structural Change and Evolution of China’s Internet Society

Startech 2 Port PCIe x4 Gbit Server Network Card

D-Link 24 Port Gigabit PoE Smart Managed Switch

D-Link 24 Port Gigabit PoE Smart Managed Switch

Power & ValueThe D-Link DGS-1250 Series Smart Managed Switches deliver real value as an Enterprise Access and Small-to-Medium Business (SMB) Access/Aggregation solution. They provide a range of physical interfaces (including a Console Port w/full CLI), multiple management interfaces, 11 Web languages, QoS enablement, and Advanced Layer-2 w/Lite Layer-3 features.The DGS-1250 Series switches support 24 or 48 x 10/100/1000BASE-T ports, with each switch also supporting an additional 4 x 10G SFP+ ports for optical connections using multimode or single-mode SFP transceivers enabling real network horsepower at a value price.Easy Maintenance, Less DowntimeThe DGS-1250 Series supports Dual Image and Dual Configuration functionality, as well as a Console Port, all of which make it easier to configure, troubleshoot, and make other changes without interfering with network operation, while full Command Line Interface (CLI) functionality enables remote configuration, without the need for the Internet. And if a network issue ever does occur, the supported Spanning Tree Protocols (STP/RSTP/MSTP) help keep things running without interruptions or downtime.Automatic ConfigurationThe DGS-1250 Series supports Auto Voice VLAN and Surveillance Mode, which allow Voice and Video traffic to be automatically identified and handled differently from regular network traffic. Auto Voice VLAN detects Voice over IP (VoIP) traffic and automatically segments it from the rest of the network, increasing security and allowing Quality of Service (QoS) to be applied.High PoE Budget (370W)The DGS-1250 series offers Power-over-Ethernet (PoE), which simplifies deployment with IP cameras, VoIP phones, Wireless Access Points, and other powered devices. Using the switchs management interface, an administrator can control various PoE functions, such as remotely rebooting Cameras or Access Points, from anywhere on the network, including over the Internet. All PoE models support the IEEE 802.3af and 802.3at standards, and each PoE power budget varies per model.Extensive Management and Advanced FeaturesThe DGS-1250 Series comes with IGMP snooping, Port Mirroring, Spanning Tree Protocol (STP), and Link Aggregation Control Protocol (LACP). The IEEE 802.3x Flow Control function allows servers to directly connect to the switch for fast, reliable data transfers. The series also supports advanced features such as Static Routing, which allows for communication between different user groups in different VLAN segments in a network.Management VersatilityThe DGS-1250 Series comes with the D-Link Network Assistant (DNA) utility so admins can remotely control their network to the port level. DNA allows customers to easily discover multiple D-Link Smart Managed Switches within the same L2 network segment and display them onscreen for instant access.

GBP 599.99
1