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A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery

A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery

The development of suitable assays the integration of appropriate technology and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor. However few scientists have the multidisciplinary experience needed to control all aspects of an HTS drug discovery project. A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery integrates the experience of diverse experts who offer fundamental and practical guidance across numerous situations. The book first discusses assay developments for important target classes such as protein kinases and phosphatases proteases nuclear receptors G protein-coupled receptors ion channels and heat shock proteins. It next examines assay developments for cell viability apoptosis and infectious diseases. The contributors explore the application of emerging technologies and systems including image-based high content screening RNA interference and primary cells. Finally they discuss the essential components of the integrated HTS process such as screening automation compound library management the screening of natural products from botanical sources and screening informatics. Designed to motivate researchers to bring further advances to the field this volume provides practical guidance on how to initiate validate optimize and manage a bioassay intended to screen large collections of compounds. Drawing on the knowledge from experts actively involved in assay development and HTS this is a resource that is both comprehensive and focused.

GBP 59.99
1

Bamboo Screening Panel 2 x 3m

Bamboo Screening Panel 2 x 3m

Bamboo screening panels are ideal to attach to existing garden fences, wire link fencing, chain fencing, arbours and pergolas, and many other areas the garden that would benefit from screening or shade. It can be easily attached to wooden garden posts and fencing, securing top and bottom of the bamboo screening panel. This bamboo screening panel is ideal for concealing unsightly existing walls, fencing, compost heaps or recycle bins. When used over arbours and pergolas, it creates soft shaded areas beneath. The versatility of this panel offers a variety of uses around the garden by just adding a natural decoration to your home and garden. Approximate Dimensions: H 2 x L 3m1 x Listed item supplied only

GBP 19.99
1

1 x 3m Bamboo Screening Panel

1 x 3m Bamboo Screening Panel

Bamboo screening panels are ideal to attach to existing garden fences, wire link fencing, chain fencing, arbours and pergolas, and many other areas the garden that would benefit from screening or shade. It can be easily attached to wooden garden posts and fencing, securing top and bottom of the bamboo screening panel. This bamboo screening panel is ideal for concealing unsightly existing walls, fencing, compost heaps or recycle bins. When used over arbours and pergolas, it creates soft shaded areas beneath. The versatility of this panel offers a variety of uses around the garden by just adding a natural decoration to your home and garden.Approximate dimensions: H 1 x L 3mExplore more of our range, we have a huge variety of products in stock. Have a query or can't find something you're looking for? We receive new deliveries every week, so if the item you wish to purchase is currently out of stock, please contact our Customer Services Team and we may be able to reserve the items you require.1 x Listed item supplied only

GBP 9.99
1

Reed Screening Panel 1 x 3m

Reed Screening Panel 1 x 3m

Reed screening panels are ideal to attach to existing garden fences, wire link fencing, chain fencing, arbours and pergolas, and many other areas the garden that would benefit from screening or shade. It can be easily attached to wooden garden posts and fencing, securing top and bottom of the Reed screening panel. This Reed screening panel is ideal for concealing unsightly existing walls, fencing, compost heaps or recycle bins. When used over arbours and pergolas, it creates soft shaded areas beneath. The versatility of this panel offers a variety of uses around the garden by just adding a natural decoration to your home and garden.Approximate dimensions: H 1 x L 3mExplore more of our range, we have a huge variety of products in stock. Have a query or can't find something you're looking for? We receive new deliveries every week, so if the item you wish to purchase is currently out of stock, please contact our Customer Services Team and we may be able to reserve the items you require.

GBP 5.99
1

1 x 3m Bamboo Screening Panel

1 x 3m Bamboo Screening Panel

Bamboo screening panels are ideal to attach to existing garden fences, wire link fencing, chain fencing, arbours and pergolas, and many other areas the garden that would benefit from screening or shade. It can be easily attached to wooden garden posts and fencing, securing top and bottom of the bamboo screening panel. This bamboo screening panel is ideal for concealing unsightly existing walls, fencing, compost heaps or recycle bins. When used over arbours and pergolas, it creates soft shaded areas beneath. The versatility of this panel offers a variety of uses around the garden by just adding a natural decoration to your home and garden. Approximate dimensions: H 1 x L 3m Explore more of our range, we have a huge variety of products in stock. Have a query or can't find something you're looking for? We receive new deliveries every week, so if the item you wish to purchase is currently out of stock, please contact our Customer Services Team and we may be able to reserve the items you require. 1 x Listed item supplied only

GBP 14.99
1

Reed Screening Panel 1 x 3m

Reed Screening Panel 1 x 3m

Reed screening panels are ideal to attach to existing garden fences, wire link fencing, chain fencing, arbours and pergolas, and many other areas the garden that would benefit from screening or shade. It can be easily attached to wooden garden posts and fencing, securing top and bottom of the Reed screening panel. This Reed screening panel is ideal for concealing unsightly existing walls, fencing, compost heaps or recycle bins. When used over arbours and pergolas, it creates soft shaded areas beneath. The versatility of this panel offers a variety of uses around the garden by just adding a natural decoration to your home and garden. Approximate dimensions: H 1 x L 3m Explore more of our range, we have a huge variety of products in stock. Have a query or can't find something you're looking for? We receive new deliveries every week, so if the item you wish to purchase is currently out of stock, please contact our Customer Services Team and we may be able to reserve the items you require.

GBP 9.99
1