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Large Multi Dose Pill Box

Etac Feed Dose Mug

Bio Productions BD Bio Dose Grease Trap & Drain Maintainer 5L 2 x 5 Litre

Bio Productions BD Bio Dose Grease Trap & Drain Maintainer 5L 2 x 5 Litre

Bio Productions BD Bio Dose Grease Trap & Drain Maintainer Bio Dose is a stable liquid containing the same selected microorganisms and enzymes as Bio Clear that efficiently reduce the waste typically evacuated into the drainage systems of kitchens and other catering and food processing units. Bio Dose is suitable for use in all types of drains, sinks and small bore pipes, as well as for maintaining septic tanks, grease traps and complete sewerage systems. Bio Dose has a two stage operation. When activated with water, the free enzymes quickly break down the waste into smaller pieces, which are more accessible to the microorganisms. This initial degradation immediately improves the drain flow rates and reduces odours. It also enables the various strains of microorganisms in Bio Dose to quickly continue the degrading process, further reducing the smaller particles of solid waste (such as fat, paper, and vegetable trimmings) into liquids and gases. - Degrades grease and solid waste - Neutral pH of 6.57.5 - Effective on all types of drains and small bore pipes - Maintains septic tanks, grease traps and complete sewerage systems - Reduces odours - Improves drain flow rates - No harmful properties Instruction Manual - Small amounts (50ml) should be poured or pumped directly into sink outlets and left overnight to unblock small bore pipework. - To maintain the grease trap, apply 1ml per meal per day into waste outlets to the trap. For best results use an automatic dosing system. - Delivered regularly through an automatic timed pump into the drain system where fats and grease enter maximises the efficacy of Bio Dose by treating fatty waste as it enters the drain. - Bio Dose is economical in use and should be dosed at a ratio of 25 litres per month in a typical catering unit or restaurant. - This divides it into approx. - 833ml per day

GBP 52.99
1

Weekly Four Dose Pill Organiser

Radiopharmaceuticals Introduction to Drug Evaluation and Dose Estimation

Radiopharmaceuticals Introduction to Drug Evaluation and Dose Estimation

Nanoengineering energized by the desire to find specific targeting agents is leading to dramatic acceleration in novel drug design. However in this flurry of activity some issues may be overlooked. This is especially true in the area of determining dosage and evaluating the effects of multiple agents designed to target more than one site of metastasis. Offering the unique perspective of a medical physicist who has worked directly with cancer patients for over three decades Radiopharmaceuticals: Introduction to Drug Evaluation and Dose Estimation starts by exploring the recent history and current state of the field. Then citing key research and practical examples the author looks at how to run studies and employ estimation and evaluation methods that lead to the best multiple agents with the least amount of trial and error. He discusses methods that will allow researchers to more rigorously:Differentiate one radiopharmaceutical (RP) from anotherEstimate radiation doses Correlate results across various species to realize more informed data from clinical trialsIncorporating developments in nanotechnology and radiology with the ultimate goal of achieving personalized patient-specific treatment this book crosses disciplines to addresses a range of topics including:Preclinical RP developmentOrganization of clinical trials Determination of activity in vivo Modeling and temporal integration with a look at the mass law for tumor uptake as a function of tumor size (discovered by the author) Absorbed dose estimates with and without clinical correlations Multiple-modality therapyDr. Lawrence Williams has devoted most of his life’s research to tumor detection and treatment and his discoveries continue to influence evolving therapies. As s a medical physicist he is eminently qualified to bring unique insight into the discussion of radiopharmaceutical dosage rates and efficacy. | Radiopharmaceuticals Introduction to Drug Evaluation and Dose Estimation

GBP 44.99
1

Model-Assisted Bayesian Designs for Dose Finding and Optimization Methods and Applications

Model-Assisted Bayesian Designs for Dose Finding and Optimization Methods and Applications

Bayesian adaptive designs provide a critical approach to improve the efficiency and success of drug development that has been embraced by the US Food and Drug Administration (FDA). This is particularly important for early phase trials as they form the basis for the development and success of subsequent phase II and III trials. The objective of this book is to describe the state-of-the-art model-assisted designs to facilitate and accelerate the use of novel adaptive designs for early phase clinical trials. Model-assisted designs possess avant-garde features where superiority meets simplicity. Model-assisted designs enjoy exceptional performance comparable to more complicated model-based adaptive designs yet their decision rules often can be pre-tabulated and included in the protocol—making implementation as simple as conventional algorithm-based designs. An example is the Bayesian optimal interval (BOIN) design the first dose-finding design to receive the fit-for-purpose designation from the FDA. This designation underscores the regulatory agency's support of the use of the novel adaptive design to improve drug development. Features Represents the first book to provide comprehensive coverage of model-assisted designs for various types of dose-finding and optimization clinical trials Describes the up-to-date theory and practice for model-assisted designs Presents many practical challenges issues and solutions arising from early-phase clinical trials Illustrates with many real trial applications Offers numerous tips and guidance on designing dose finding and optimization trials Provides step-by-step illustrations of using software to design trials Develops a companion website (www. trialdesign. org) to provide freely available easy-to-use software to assist learning and implementing model-assisted designs Written by internationally recognized research leaders who pioneered model-assisted designs from the University of Texas MD Anderson Cancer Center this book shows how model-assisted designs can greatly improve the efficiency and simplify the design conduct and optimization of early-phase dose-finding trials. It should therefore be a very useful practical reference for biostatisticians clinicians working in clinical trials and drug regulatory professionals as well as graduate students of biostatistics. Novel model-assisted designs showcase the new KISS principle: Keep it simple and smart! | Model-Assisted Bayesian Designs for Dose Finding and Optimization Methods and Applications

GBP 84.99
1

Alpha-H Women's Daily Dose Multivitamin Body Serum 150ml - Available at M&S

Tradefrog 2.27 Super Dose Bactericidal Multi-purpose Cleaner - 6 x 1L

*Display Model* Samsung Series 6 WW90T634DLH 9Kg Freestanding Auto Dose Washing Machine|9kg 1400rpm - White